BDBM50119903 2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,2,4-trimethyl-3,4-dihydro-2H-quinolin-1-yl)-ethanone::CHEMBL104160

SMILES: CC1CC(C)(C)N(C(=O)CN2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12

InChI Key: InChIKey=IHQUTAVKEAOLLM-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119903 (2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,2,4-tr...) Show SMILES CC1CC(C)(C)N(C(=O)CN2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C25H32ClN3O/c1-19-16-25(2,3)29(23-7-5-4-6-22(19)23)24(30)18-28-14-12-27(13-15-28)17-20-8-10-21(26)11-9-20/h4-11,19H,12-18H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards human Dopamine receptor D2 was determined via standard competitive displacement assay using [3H]-YM 09151 as radioligand				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50119903 (2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,2,4-tr...) Show SMILES CC1CC(C)(C)N(C(=O)CN2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C25H32ClN3O/c1-19-16-25(2,3)29(23-7-5-4-6-22(19)23)24(30)18-28-14-12-27(13-15-28)17-20-8-10-21(26)11-9-20/h4-11,19H,12-18H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards human Dopamine Receptor D4 was determined via standard competitive displacement assays using [3H]-YM 09151 as radioligand				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50119903 (2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-(2,2,4-tr...) Show SMILES CC1CC(C)(C)N(C(=O)CN2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C25H32ClN3O/c1-19-16-25(2,3)29(23-7-5-4-6-22(19)23)24(30)18-28-14-12-27(13-15-28)17-20-8-10-21(26)11-9-20/h4-11,19H,12-18H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards Alpha-1 adrenergic receptor via standard competitive displacement assay using rat brain homogenate with [3H]prazosin as radi...				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair