BDBM50119913 2-[4-(2-Methoxy-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL321734

SMILES: COc1ccccc1CN1CCN(CC(=O)N2C(C)Cc3ccccc23)CC1

InChI Key: InChIKey=RMVOSVURGLWXST-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50119913 (2-[4-(2-Methoxy-benzyl)-piperazin-1-yl]-1-(2-methy...) Show SMILES COc1ccccc1CN1CCN(CC(=O)N2C(C)Cc3ccccc23)CC1 Show InChI InChI=1S/C23H29N3O2/c1-18-15-19-7-3-5-9-21(19)26(18)23(27)17-25-13-11-24(12-14-25)16-20-8-4-6-10-22(20)28-2/h3-10,18H,11-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards human dopamine D4 receptor was determined via standard competitive displacement assays using [3H]-YM 09151 as radioligand				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119913 (2-[4-(2-Methoxy-benzyl)-piperazin-1-yl]-1-(2-methy...) Show SMILES COc1ccccc1CN1CCN(CC(=O)N2C(C)Cc3ccccc23)CC1 Show InChI InChI=1S/C23H29N3O2/c1-18-15-19-7-3-5-9-21(19)26(18)23(27)17-25-13-11-24(12-14-25)16-20-8-4-6-10-22(20)28-2/h3-10,18H,11-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards human dopamine D2 receptor, using [3H]-YM-09151 as a radioligand				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50119913 (2-[4-(2-Methoxy-benzyl)-piperazin-1-yl]-1-(2-methy...) Show SMILES COc1ccccc1CN1CCN(CC(=O)N2C(C)Cc3ccccc23)CC1 Show InChI InChI=1S/C23H29N3O2/c1-18-15-19-7-3-5-9-21(19)26(18)23(27)17-25-13-11-24(12-14-25)16-20-8-4-6-10-22(20)28-2/h3-10,18H,11-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Dopamine D4 receptor functional activity was assessed via inhibition of quinpirole stimulated [35S]-GTP-gammaS binding from cell membranes.				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair