BDBM50120098 CHEMBL322598::N*4*-(2-Chloro-6-methyl-phenyl)-8-methoxy-N*7*-(2-morpholin-4-yl-ethyl)-imidazo[1,5-a]quinoxaline-4,7-diamine::N4-(2-chloro-6-methylphenyl)-8-methoxy-N7-(2-morpholinoethyl)imidazo[1,5-a]quinoxaline-4,7-diamine

SMILES: COc1cc2c(cc1NCCN1CCOCC1)nc(Nc1c(C)cccc1Cl)c1cncn21

InChI Key: InChIKey=UBAMOLBWSOXUPW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50120098 (CHEMBL322598 | N*4*-(2-Chloro-6-methyl-phenyl)-8-m...) Show SMILES COc1cc2c(cc1NCCN1CCOCC1)nc(Nc1c(C)cccc1Cl)c1cncn21 Show InChI InChI=1S/C24H27ClN6O2/c1-16-4-3-5-17(25)23(16)29-24-21-14-26-15-31(21)20-13-22(32-2)19(12-18(20)28-24)27-6-7-30-8-10-33-11-9-30/h3-5,12-15,27H,6-11H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1179-88 (2008) Article DOI: 10.1021/jm070654j BindingDB Entry DOI: 10.7270/Q29Z95RD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50120098 (CHEMBL322598 | N*4*-(2-Chloro-6-methyl-phenyl)-8-m...) Show SMILES COc1cc2c(cc1NCCN1CCOCC1)nc(Nc1c(C)cccc1Cl)c1cncn21 Show InChI InChI=1S/C24H27ClN6O2/c1-16-4-3-5-17(25)23(16)29-24-21-14-26-15-31(21)20-13-22(32-2)19(12-18(20)28-24)27-6-7-30-8-10-33-11-9-30/h3-5,12-15,27H,6-11H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description 50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.				Bioorg Med Chem Lett 12: 3153-6 (2002) BindingDB Entry DOI: 10.7270/Q2NC60JR
					More data for this Ligand-Target Pair