BDBM50120099 (2-Chloro-6-methyl-phenyl)-(9-methoxy-imidazo[1,5-a]quinoxalin-4-yl)-amine::CHEMBL106378::N-(2-chloro-6-methylphenyl)-9-methoxyimidazo[1,5-a]quinoxalin-4-amine

SMILES: COc1cccc2nc(Nc3c(C)cccc3Cl)c3cncn3c12

InChI Key: InChIKey=NWSYOBUIPKAVEH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50120099 ((2-Chloro-6-methyl-phenyl)-(9-methoxy-imidazo[1,5-...) Show SMILES COc1cccc2nc(Nc3c(C)cccc3Cl)c3cncn3c12 Show InChI InChI=1S/C18H15ClN4O/c1-11-5-3-6-12(19)16(11)22-18-14-9-20-10-23(14)17-13(21-18)7-4-8-15(17)24-2/h3-10H,1-2H3,(H,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1179-88 (2008) Article DOI: 10.1021/jm070654j BindingDB Entry DOI: 10.7270/Q29Z95RD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50120099 ((2-Chloro-6-methyl-phenyl)-(9-methoxy-imidazo[1,5-...) Show SMILES COc1cccc2nc(Nc3c(C)cccc3Cl)c3cncn3c12 Show InChI InChI=1S/C18H15ClN4O/c1-11-5-3-6-12(19)16(11)22-18-14-9-20-10-23(14)17-13(21-18)7-4-8-15(17)24-2/h3-10H,1-2H3,(H,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description 50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.				Bioorg Med Chem Lett 12: 3153-6 (2002) BindingDB Entry DOI: 10.7270/Q2NC60JR
					More data for this Ligand-Target Pair