null

SMILES: CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(OC)nc1

InChI Key: InChIKey=YPIUGMFQHBZWOR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50120367 (CHEMBL3616695) Show SMILES CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(OC)nc1 Show InChI InChI=1S/C36H35F3N4O5/c1-4-5-6-29(22-7-9-23(10-8-22)35(46)40-18-17-33(44)45)43-30-19-24(25-12-16-32(48-3)41-21-25)11-14-27(30)34(42-43)28-20-26(36(37,38)39)13-15-31(28)47-2/h7-16,19-21,29H,4-6,17-18H2,1-3H3,(H,40,46)(H,44,45)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120367 (CHEMBL3616695) Show SMILES CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(OC)nc1 Show InChI InChI=1S/C36H35F3N4O5/c1-4-5-6-29(22-7-9-23(10-8-22)35(46)40-18-17-33(44)45)43-30-19-24(25-12-16-32(48-3)41-21-25)11-14-27(30)34(42-43)28-20-26(36(37,38)39)13-15-31(28)47-2/h7-16,19-21,29H,4-6,17-18H2,1-3H3,(H,40,46)(H,44,45)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP production				Bioorg Med Chem Lett 25: 4143-7 (2015) BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair