BDBM50120626 CHEMBL3618331

SMILES: OC1CN(C1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=WVDWBRFTMSOBSU-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50120626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GPR24 (RAT)	BDBM50120626 (CHEMBL3618331) Show SMILES OC1CN(C1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H16ClN5O2/c21-15-3-1-13(2-4-15)14-7-18-20(28)25(12-23-26(18)9-14)16-5-6-19(22-8-16)24-10-17(27)11-24/h1-9,12,17,27H,10-11H2	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Displacement of [125I][Phe13,Tyr19]-MCH from rat MCHR1 by scintillation counting analysis				Bioorg Med Chem Lett 25: 4412-8 (2015) BindingDB Entry DOI: 10.7270/Q2JD4ZMW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50120626 (CHEMBL3618331) Show SMILES OC1CN(C1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H16ClN5O2/c21-15-3-1-13(2-4-15)14-7-18-20(28)25(12-23-26(18)9-14)16-5-6-19(22-8-16)24-10-17(27)11-24/h1-9,12,17,27H,10-11H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Displacement of [125I][Phe13,Tyr19]-MCH from human MCHR1 expressed in HEK293 cells by scintillation counting analysis				Bioorg Med Chem Lett 25: 4412-8 (2015) BindingDB Entry DOI: 10.7270/Q2JD4ZMW
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50120626 (CHEMBL3618331) Show SMILES OC1CN(C1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H16ClN5O2/c21-15-3-1-13(2-4-15)14-7-18-20(28)25(12-23-26(18)9-14)16-5-6-19(22-8-16)24-10-17(27)11-24/h1-9,12,17,27H,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human ERG by flux assay				Bioorg Med Chem Lett 25: 4412-8 (2015) BindingDB Entry DOI: 10.7270/Q2JD4ZMW
					More data for this Ligand-Target Pair