BDBM50120692 2-{3-[4-(3,5-Dimethyl-benzyloxy)-phenyl]-3-methyl-2-oxo-pyrrolidin-1-yl}-N-hydroxy-propionamide::CHEMBL144548

SMILES: C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)cc(C)c2)cc1)C(=O)NO

InChI Key: InChIKey=AHGKFZKBVGBMPT-HXOBKFHXSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50120692 (2-{3-[4-(3,5-Dimethyl-benzyloxy)-phenyl]-3-methyl-...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)cc(C)c2)cc1)C(=O)NO Show InChI InChI=1S/C23H28N2O4/c1-15-11-16(2)13-18(12-15)14-29-20-7-5-19(6-8-20)23(4)9-10-25(22(23)27)17(3)21(26)24-28/h5-8,11-13,17,28H,9-10,14H2,1-4H3,(H,24,26)/t17-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity towards Matrix metalloprotease-9 (MMP-9)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50120692 (2-{3-[4-(3,5-Dimethyl-benzyloxy)-phenyl]-3-methyl-...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)cc(C)c2)cc1)C(=O)NO Show InChI InChI=1S/C23H28N2O4/c1-15-11-16(2)13-18(12-15)14-29-20-7-5-19(6-8-20)23(4)9-10-25(22(23)27)17(3)21(26)24-28/h5-8,11-13,17,28H,9-10,14H2,1-4H3,(H,24,26)/t17-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity towards Matrix metalloprotease-1 (MMP-1)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50120692 (2-{3-[4-(3,5-Dimethyl-benzyloxy)-phenyl]-3-methyl-...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)cc(C)c2)cc1)C(=O)NO Show InChI InChI=1S/C23H28N2O4/c1-15-11-16(2)13-18(12-15)14-29-20-7-5-19(6-8-20)23(4)9-10-25(22(23)27)17(3)21(26)24-28/h5-8,11-13,17,28H,9-10,14H2,1-4H3,(H,24,26)/t17-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity for Matrix metalloprotease-2 (MMP-2)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig))	BDBM50120692 (2-{3-[4-(3,5-Dimethyl-benzyloxy)-phenyl]-3-methyl-...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)cc(C)c2)cc1)C(=O)NO Show InChI InChI=1S/C23H28N2O4/c1-15-11-16(2)13-18(12-15)14-29-20-7-5-19(6-8-20)23(4)9-10-25(22(23)27)17(3)21(26)24-28/h5-8,11-13,17,28H,9-10,14H2,1-4H3,(H,24,26)/t17-,23+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity for Tumor necrosis factor alpha converting enzyme (TACE)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair