BDBM50120760 CHEMBL343256::Cyclohexanecarboxylic acid (7-methyl-2-phenyl-imidazo[1,2-a][1,3,5]triazin-4-yl)-amide

SMILES: Cc1cn2c(NC(=O)C3CCCCC3)nc(nc2n1)-c1ccccc1

InChI Key: InChIKey=AAZSAJNRFPVZLB-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine A1 receptor (BOVINE)	BDBM50120760 (CHEMBL343256 | Cyclohexanecarboxylic acid (7-methy...) Show SMILES Cc1cn2c(NC(=O)C3CCCCC3)nc(nc2n1)-c1ccccc1 Show InChI InChI=1S/C19H21N5O/c1-13-12-24-18(20-13)21-16(14-8-4-2-5-9-14)22-19(24)23-17(25)15-10-6-3-7-11-15/h2,4-5,8-9,12,15H,3,6-7,10-11H2,1H3,(H,20,21,22,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	116	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Chemistry, School of Pharmacy, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa. Curated by ChEMBL					Assay Description Displacement of [3H]CHA from A1 receptor in bovine cortical membrane				Bioorg Med Chem Lett 27: 3963-3967 (2017) Article DOI: 10.1016/j.bmcl.2017.07.071 BindingDB Entry DOI: 10.7270/Q2BZ68J4
					More data for this Ligand-Target Pair
Adenosine A1 receptor (BOVINE)	BDBM50120760 (CHEMBL343256 | Cyclohexanecarboxylic acid (7-methy...) Show SMILES Cc1cn2c(NC(=O)C3CCCCC3)nc(nc2n1)-c1ccccc1 Show InChI InChI=1S/C19H21N5O/c1-13-12-24-18(20-13)21-16(14-8-4-2-5-9-14)22-19(24)23-17(25)15-10-6-3-7-11-15/h2,4-5,8-9,12,15H,3,6-7,10-11H2,1H3,(H,20,21,22,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	116	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.				J Med Chem 45: 5030-6 (2002) BindingDB Entry DOI: 10.7270/Q2JH3KHN
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50120760 (CHEMBL343256 | Cyclohexanecarboxylic acid (7-methy...) Show SMILES Cc1cn2c(NC(=O)C3CCCCC3)nc(nc2n1)-c1ccccc1 Show InChI InChI=1S/C19H21N5O/c1-13-12-24-18(20-13)21-16(14-8-4-2-5-9-14)22-19(24)23-17(25)15-10-6-3-7-11-15/h2,4-5,8-9,12,15H,3,6-7,10-11H2,1H3,(H,20,21,22,23,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	202	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [125I]-AB-MECA from Adenosine A3 receptor in bovine cortical membranes in the presence of 20 nM DPCPX.				J Med Chem 45: 5030-6 (2002) BindingDB Entry DOI: 10.7270/Q2JH3KHN
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50120760 (CHEMBL343256 | Cyclohexanecarboxylic acid (7-methy...) Show SMILES Cc1cn2c(NC(=O)C3CCCCC3)nc(nc2n1)-c1ccccc1 Show InChI InChI=1S/C19H21N5O/c1-13-12-24-18(20-13)21-16(14-8-4-2-5-9-14)22-19(24)23-17(25)15-10-6-3-7-11-15/h2,4-5,8-9,12,15H,3,6-7,10-11H2,1H3,(H,20,21,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]- CGS-21,680 from Adenosine A2a receptor in bovine striatal membranes.				J Med Chem 45: 5030-6 (2002) BindingDB Entry DOI: 10.7270/Q2JH3KHN
					More data for this Ligand-Target Pair