BDBM50120802 CHEMBL3100130
SMILES: [H][C@@]1(O[C@H](C)CCc2ccc(O)cc2O)O[C@H](CO)[C@@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O
InChI Key: InChIKey=ZRDADUROYMLJRH-DMISBUROSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50120802 (CHEMBL3100130) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Agriculture and Technology Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometry | Bioorg Med Chem Lett 24: 122-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.063 BindingDB Entry DOI: 10.7270/Q2NZ8BMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Homo sapiens (Human)) | BDBM50120802 (CHEMBL3100130) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Agriculture and Technology Curated by ChEMBL | Assay Description Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis | Bioorg Med Chem 23: 6650-8 (2015) BindingDB Entry DOI: 10.7270/Q2DR2X9W | |||||||||||
More data for this Ligand-Target Pair |