BDBM50120992 CHEMBL3621445

SMILES: COc1nc(nc(OC)c1NC(=O)CC(C)(C)C)N1CCC(CC1)OC(C)C

InChI Key: InChIKey=GGVSCRINGSNJFB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv7.2/Kv7.3 (Homo sapiens (Human))	BDBM50120992 (CHEMBL3621445) Show SMILES COc1nc(nc(OC)c1NC(=O)CC(C)(C)C)N1CCC(CC1)OC(C)C Show InChI InChI=1S/C20H34N4O4/c1-13(2)28-14-8-10-24(11-9-14)19-22-17(26-6)16(18(23-19)27-7)21-15(25)12-20(3,4)5/h13-14H,8-12H2,1-7H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	358	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human Kv7.2/7.3 expressed in CHOK1 cells				Bioorg Med Chem Lett 25: 4941-4 (2015) BindingDB Entry DOI: 10.7270/Q28054FG
					More data for this Ligand-Target Pair