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SMILES: CCOC(=O)CNC(=O)C1CCN(CCOc2ccc(Cc3ccccc3)cc2)CC1

InChI Key: InChIKey=OXYVGECAKLAUMO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121019   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50121019
PNG
(({1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine-4-carb...)
Show SMILES CCOC(=O)CNC(=O)C1CCN(CCOc2ccc(Cc3ccccc3)cc2)CC1
Show InChI InChI=1S/C25H32N2O4/c1-2-30-24(28)19-26-25(29)22-12-14-27(15-13-22)16-17-31-23-10-8-21(9-11-23)18-20-6-4-3-5-7-20/h3-11,22H,2,12-19H2,1H3,(H,26,29)
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Similars
PubMed
n/an/a 110n/an/an/an/an/an/a



Pharmacia Corporation

Curated by ChEMBL


Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay

Bioorg Med Chem Lett 12: 3383-6 (2002)


BindingDB Entry DOI: 10.7270/Q2N8795W
More data for this
Ligand-Target Pair