BDBM50121050 CHEMBL3621798

SMILES: COC1CCN(CC1)c1nc(OC)c(NC(=O)CC(C)C)c(OC)n1

InChI Key: InChIKey=WLRCFJPLUWMENY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv7.2/Kv7.3 (Homo sapiens (Human))	BDBM50121050 (CHEMBL3621798) Show SMILES COC1CCN(CC1)c1nc(OC)c(NC(=O)CC(C)C)c(OC)n1 Show InChI InChI=1S/C17H28N4O4/c1-11(2)10-13(22)18-14-15(24-4)19-17(20-16(14)25-5)21-8-6-12(23-3)7-9-21/h11-12H,6-10H2,1-5H3,(H,18,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	630	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human Kv7.2/7.3 expressed in CHOK1 cells				Bioorg Med Chem Lett 25: 4941-4 (2015) BindingDB Entry DOI: 10.7270/Q28054FG
					More data for this Ligand-Target Pair