null

SMILES: Cc1cc2c(cc1Cc1ccc(o1)C(=O)NCC1CCN(CC1)C(N)=N)C(C)(C)CCC2(C)C

InChI Key: InChIKey=LSBNEHCBBLNSAV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50121102 (5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...) Show SMILES Cc1cc2c(cc1Cc1ccc(o1)C(=O)NCC1CCN(CC1)C(N)=N)C(C)(C)CCC2(C)C Show InChI InChI=1S/C28H40N4O2/c1-18-14-22-23(28(4,5)11-10-27(22,2)3)16-20(18)15-21-6-7-24(34-21)25(33)31-17-19-8-12-32(13-9-19)26(29)30/h6-7,14,16,19H,8-13,15,17H2,1-5H3,(H3,29,30)(H,31,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-La Jolla/Agouron Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity to human gonadotropin-releasing hormone receptor				Bioorg Med Chem Lett 12: 3467-70 (2002) BindingDB Entry DOI: 10.7270/Q20K27X7
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50121102 (5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...) Show SMILES Cc1cc2c(cc1Cc1ccc(o1)C(=O)NCC1CCN(CC1)C(N)=N)C(C)(C)CCC2(C)C Show InChI InChI=1S/C28H40N4O2/c1-18-14-22-23(28(4,5)11-10-27(22,2)3)16-20(18)15-21-6-7-24(34-21)25(33)31-17-19-8-12-32(13-9-19)26(29)30/h6-7,14,16,19H,8-13,15,17H2,1-5H3,(H3,29,30)(H,31,33)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-La Jolla/Agouron Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to rat gonadotropin-releasing hormone receptor				Bioorg Med Chem Lett 12: 3467-70 (2002) BindingDB Entry DOI: 10.7270/Q20K27X7
					More data for this Ligand-Target Pair