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SMILES: CCC1C(=O)Nc2ccc(cc12)-c1cccc(Cl)c1

InChI Key: InChIKey=FPXSSMRJZOTADU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121181   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))		BDBM50121181
PNG
(5-(3-Chloro-phenyl)-3-ethyl-1,3-dihydro-indol-2-on...)
Show SMILES CCC1C(=O)Nc2ccc(cc12)-c1cccc(Cl)c1
Show InChI InChI=1S/C16H14ClNO/c1-2-13-14-9-11(6-7-15(14)18-16(13)19)10-4-3-5-12(17)8-10/h3-9,13H,2H2,1H3,(H,18,19)
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PubMed
n/an/a 130n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...

Bioorg Med Chem Lett 12: 3487-90 (2002)


BindingDB Entry DOI: 10.7270/Q2R210RC
More data for this
Ligand-Target Pair