BDBM50121410 CHEMBL420525::Lithium; 2-(2,4-dichloro-benzoylamino)-5-(2-pyridin-2-yl-ethoxy)-benzoate

SMILES: [O-]C(=O)c1cc(OCCc2ccccn2)ccc1NC(=O)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=KPVYCWCEYPSTHH-UHFFFAOYSA-M

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50121410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50121410 (CHEMBL420525 | Lithium; 2-(2,4-dichloro-benzoylami...) Show SMILES [O-]C(=O)c1cc(OCCc2ccccn2)ccc1NC(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H16Cl2N2O4/c22-13-4-6-16(18(23)11-13)20(26)25-19-7-5-15(12-17(19)21(27)28)29-10-8-14-3-1-2-9-24-14/h1-7,9,11-12H,8,10H2,(H,25,26)(H,27,28)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biovitrum AB Curated by ChEMBL					Assay Description Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...				Bioorg Med Chem Lett 12: 3565-7 (2002) BindingDB Entry DOI: 10.7270/Q2Q23ZK5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50121410 (CHEMBL420525 | Lithium; 2-(2,4-dichloro-benzoylami...) Show SMILES [O-]C(=O)c1cc(OCCc2ccccn2)ccc1NC(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H16Cl2N2O4/c22-13-4-6-16(18(23)11-13)20(26)25-19-7-5-15(12-17(19)21(27)28)29-10-8-14-3-1-2-9-24-14/h1-7,9,11-12H,8,10H2,(H,25,26)(H,27,28)/p-1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biovitrum AB Curated by ChEMBL					Assay Description Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...				Bioorg Med Chem Lett 12: 3565-7 (2002) BindingDB Entry DOI: 10.7270/Q2Q23ZK5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50121410 (CHEMBL420525 | Lithium; 2-(2,4-dichloro-benzoylami...) Show SMILES [O-]C(=O)c1cc(OCCc2ccccn2)ccc1NC(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H16Cl2N2O4/c22-13-4-6-16(18(23)11-13)20(26)25-19-7-5-15(12-17(19)21(27)28)29-10-8-14-3-1-2-9-24-14/h1-7,9,11-12H,8,10H2,(H,25,26)(H,27,28)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Biovitrum AB Curated by ChEMBL					Assay Description Transactivation potency was measured by luciferase activity in Caco- 2/TC7 cells transiently co-transfected for the fusion-protein Gal4-PPAR gamma				Bioorg Med Chem Lett 12: 3565-7 (2002) BindingDB Entry DOI: 10.7270/Q2Q23ZK5
					More data for this Ligand-Target Pair