null

SMILES: Cc1cc2c(cc1Cc1ccc(o1)C(=O)NCC1CCCC(CNc3ncccn3)C1)C(C)(C)CCC2(C)C

InChI Key: InChIKey=UNFRYQPKQNCOTR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50121468 (5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...) Show SMILES Cc1cc2c(cc1Cc1ccc(o1)C(=O)NCC1CCCC(CNc3ncccn3)C1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C33H44N4O2/c1-22-16-27-28(33(4,5)13-12-32(27,2)3)19-25(22)18-26-10-11-29(39-26)30(38)36-20-23-8-6-9-24(17-23)21-37-31-34-14-7-15-35-31/h7,10-11,14-16,19,23-24H,6,8-9,12-13,17-18,20-21H2,1-5H3,(H,36,38)(H,34,35,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-La Jolla/Agouron Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity towards human gonadotropin-releasing hormone receptor				Bioorg Med Chem Lett 12: 3635-9 (2002) BindingDB Entry DOI: 10.7270/Q2XK8DXZ
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50121468 (5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...) Show SMILES Cc1cc2c(cc1Cc1ccc(o1)C(=O)NCC1CCCC(CNc3ncccn3)C1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C33H44N4O2/c1-22-16-27-28(33(4,5)13-12-32(27,2)3)19-25(22)18-26-10-11-29(39-26)30(38)36-20-23-8-6-9-24(17-23)21-37-31-34-14-7-15-35-31/h7,10-11,14-16,19,23-24H,6,8-9,12-13,17-18,20-21H2,1-5H3,(H,36,38)(H,34,35,37)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-La Jolla/Agouron Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity towards rat gonadotropin-releasing hormone receptor				Bioorg Med Chem Lett 12: 3635-9 (2002) BindingDB Entry DOI: 10.7270/Q2XK8DXZ
					More data for this Ligand-Target Pair