null

SMILES: CN(CCCc1ccc(Cl)cc1)c1nc(NCCc2ccc(O)cc2)nc(n1)N1CCN(Cc2ccncc2)CC1

InChI Key: InChIKey=BMBRGXHCBMOLNP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor beta (Homo sapiens (Human))	BDBM50121621 (4-{2-[4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...) Show SMILES CN(CCCc1ccc(Cl)cc1)c1nc(NCCc2ccc(O)cc2)nc(n1)N1CCN(Cc2ccncc2)CC1 Show InChI InChI=1S/C31H37ClN8O/c1-38(18-2-3-24-4-8-27(32)9-5-24)30-35-29(34-17-14-25-6-10-28(41)11-7-25)36-31(37-30)40-21-19-39(20-22-40)23-26-12-15-33-16-13-26/h4-13,15-16,41H,2-3,14,17-23H2,1H3,(H,34,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligand				J Med Chem 45: 5492-505 (2002) BindingDB Entry DOI: 10.7270/Q2J965RW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50121621 (4-{2-[4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino...) Show SMILES CN(CCCc1ccc(Cl)cc1)c1nc(NCCc2ccc(O)cc2)nc(n1)N1CCN(Cc2ccncc2)CC1 Show InChI InChI=1S/C31H37ClN8O/c1-38(18-2-3-24-4-8-27(32)9-5-24)30-35-29(34-17-14-25-6-10-28(41)11-7-25)36-31(37-30)40-21-19-39(20-22-40)23-26-12-15-33-16-13-26/h4-13,15-16,41H,2-3,14,17-23H2,1H3,(H,34,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description In vitro binding affinity towards human Estrogen receptor alpha using [3H]-17-beta-estradiol as radioligand				J Med Chem 45: 5492-505 (2002) BindingDB Entry DOI: 10.7270/Q2J965RW
					More data for this Ligand-Target Pair