null
SMILES: CSc1ccc(\C=N\c2cc(ccc2O)[N+]([O-])=O)cc1
InChI Key: InChIKey=QMRCPJWGPKSHGQ-OQLLNIDSSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50121656 (CHEMBL3616869) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.51E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University Curated by ChEMBL | Assay Description Binding affinity to human CDK2 Y180A mutant expressed in Escherichia coli BL21 assessed as inhibition of interaction with cyclin A3 by measuring HHAS... | Bioorg Med Chem Lett 25: 4069-73 (2015) BindingDB Entry DOI: 10.7270/Q261123C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50121656 (CHEMBL3616869) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.85E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University Curated by ChEMBL | Assay Description Binding affinity to human CDK2 R150A mutant expressed in Escherichia coli BL21 assessed as inhibition of interaction with cyclin A3 by measuring HHAS... | Bioorg Med Chem Lett 25: 4069-73 (2015) BindingDB Entry DOI: 10.7270/Q261123C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50121656 (CHEMBL3616869) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University Curated by ChEMBL | Assay Description Binding affinity to N-terminal His-tagged recombinant human CDK2 (1 to 298 amino acid residues) expressed in Escherichia coli BL21 assessed as inhibi... | Bioorg Med Chem Lett 25: 4069-73 (2015) BindingDB Entry DOI: 10.7270/Q261123C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50121656 (CHEMBL3616869) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University Curated by ChEMBL | Assay Description Binding affinity to N-terminal His-tagged recombinant human CDK2 (1 to 298 amino acid residues) expressed in Escherichia coli BL21 assessed as inhibi... | Bioorg Med Chem Lett 25: 4069-73 (2015) BindingDB Entry DOI: 10.7270/Q261123C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50121656 (CHEMBL3616869) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University Curated by ChEMBL | Assay Description Binding affinity to N-terminal His-tagged recombinant human CDK2 (1 to 298 amino acid residues) expressed in Escherichia coli BL21 assessed as inhibi... | Bioorg Med Chem Lett 25: 4069-73 (2015) BindingDB Entry DOI: 10.7270/Q261123C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50121656 (CHEMBL3616869) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University Curated by ChEMBL | Assay Description Binding affinity to N-terminal His-tagged recombinant human CDK2 (1 to 298 amino acid residues) expressed in Escherichia coli BL21 assessed as inhibi... | Bioorg Med Chem Lett 25: 4069-73 (2015) BindingDB Entry DOI: 10.7270/Q261123C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50121656 (CHEMBL3616869) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University Curated by ChEMBL | Assay Description Binding affinity to N-terminal His-tagged recombinant human CDK2 (1 to 298 amino acid residues) expressed in Escherichia coli BL21 assessed as inhibi... | Bioorg Med Chem Lett 25: 4069-73 (2015) BindingDB Entry DOI: 10.7270/Q261123C | |||||||||||
More data for this Ligand-Target Pair |