BDBM50121847 CHEMBL3617132
SMILES: COc1cc(OC)cc(\C=C\C(=N/O)\c2cc3ccccc3cc2O)c1
InChI Key: InChIKey=DXTLPYQRXVCXMB-SMHSOALZSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50121847 (CHEMBL3617132) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Technology Sydney Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot | Bioorg Med Chem Lett 25: 4085-91 (2015) BindingDB Entry DOI: 10.7270/Q2P270ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50121847 (CHEMBL3617132) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Technology Sydney Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate | Bioorg Med Chem Lett 25: 4085-91 (2015) BindingDB Entry DOI: 10.7270/Q2P270ZQ | |||||||||||
More data for this Ligand-Target Pair |