BDBM50122341 (S)-3-[4-((E)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-phenyl]-2-ethoxy-propionic acid::CHEMBL420973

SMILES: CCO[C@@H](Cc1ccc(OC\C=C(/c2ccccc2)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O

InChI Key: InChIKey=IILKLIPGEXMTPN-CJFFBLHWSA-N

Data: 7 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50122341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50122341 ((S)-3-[4-((E)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...) Show SMILES CCO[C@@H](Cc1ccc(OC\C=C(/c2ccccc2)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C32H30O4/c1-2-35-31(32(33)34)23-24-13-19-29(20-14-24)36-22-21-30(27-11-7-4-8-12-27)28-17-15-26(16-18-28)25-9-5-3-6-10-25/h3-21,31H,2,22-23H2,1H3,(H,33,34)/b30-21+/t31-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...				Citation and Details Article DOI: 10.1007/s00044-012-0003-4 BindingDB Entry DOI: 10.7270/Q280544F
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50122341 ((S)-3-[4-((E)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...) Show SMILES CCO[C@@H](Cc1ccc(OC\C=C(/c2ccccc2)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C32H30O4/c1-2-35-31(32(33)34)23-24-13-19-29(20-14-24)36-22-21-30(27-11-7-4-8-12-27)28-17-15-26(16-18-28)25-9-5-3-6-10-25/h3-21,31H,2,22-23H2,1H3,(H,33,34)/b30-21+/t31-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...				Citation and Details Article DOI: 10.1007/s00044-012-0003-4 BindingDB Entry DOI: 10.7270/Q280544F
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50122341 ((S)-3-[4-((E)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...) Show SMILES CCO[C@@H](Cc1ccc(OC\C=C(/c2ccccc2)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C32H30O4/c1-2-35-31(32(33)34)23-24-13-19-29(20-14-24)36-22-21-30(27-11-7-4-8-12-27)28-17-15-26(16-18-28)25-9-5-3-6-10-25/h3-21,31H,2,22-23H2,1H3,(H,33,34)/b30-21+/t31-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...				Citation and Details Article DOI: 10.1007/s00044-012-0003-4 BindingDB Entry DOI: 10.7270/Q280544F
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50122341 ((S)-3-[4-((E)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...) Show SMILES CCO[C@@H](Cc1ccc(OC\C=C(/c2ccccc2)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C32H30O4/c1-2-35-31(32(33)34)23-24-13-19-29(20-14-24)36-22-21-30(27-11-7-4-8-12-27)28-17-15-26(16-18-28)25-9-5-3-6-10-25/h3-21,31H,2,22-23H2,1H3,(H,33,34)/b30-21+/t31-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro activation of human peroxisome proliferator activated receptor delta (PPAR delta)				Bioorg Med Chem Lett 13: 257-60 (2002) BindingDB Entry DOI: 10.7270/Q2FF3RQS
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50122341 ((S)-3-[4-((E)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...) Show SMILES CCO[C@@H](Cc1ccc(OC\C=C(/c2ccccc2)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C32H30O4/c1-2-35-31(32(33)34)23-24-13-19-29(20-14-24)36-22-21-30(27-11-7-4-8-12-27)28-17-15-26(16-18-28)25-9-5-3-6-10-25/h3-21,31H,2,22-23H2,1H3,(H,33,34)/b30-21+/t31-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro activation of human peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 13: 257-60 (2002) BindingDB Entry DOI: 10.7270/Q2FF3RQS
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50122341 ((S)-3-[4-((E)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...) Show SMILES CCO[C@@H](Cc1ccc(OC\C=C(/c2ccccc2)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C32H30O4/c1-2-35-31(32(33)34)23-24-13-19-29(20-14-24)36-22-21-30(27-11-7-4-8-12-27)28-17-15-26(16-18-28)25-9-5-3-6-10-25/h3-21,31H,2,22-23H2,1H3,(H,33,34)/b30-21+/t31-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro activation of human peroxisome proliferator activated receptor gamma (PPAR gamma)				Bioorg Med Chem Lett 13: 257-60 (2002) BindingDB Entry DOI: 10.7270/Q2FF3RQS
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50122341 ((S)-3-[4-((E)-3-Biphenyl-4-yl-3-phenyl-allyloxy)-p...) Show SMILES CCO[C@@H](Cc1ccc(OC\C=C(/c2ccccc2)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C32H30O4/c1-2-35-31(32(33)34)23-24-13-19-29(20-14-24)36-22-21-30(27-11-7-4-8-12-27)28-17-15-26(16-18-28)25-9-5-3-6-10-25/h3-21,31H,2,22-23H2,1H3,(H,33,34)/b30-21+/t31-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...				Citation and Details Article DOI: 10.1007/s00044-012-0003-4 BindingDB Entry DOI: 10.7270/Q280544F
					More data for this Ligand-Target Pair