BDBM50122605 4,6-Dichloro-3-(3-cyclohexyl-2,4-dioxo-imidazolidin-1-ylmethyl)-1H-indole-2-carboxylic acid::CHEMBL354003

SMILES: OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1Cn1cc(O)n(C2CCCCC2)c1=O

InChI Key: InChIKey=FEIVYLJBUPTGLJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50122605 (4,6-Dichloro-3-(3-cyclohexyl-2,4-dioxo-imidazolidi...) Show SMILES OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1Cn1cc(O)n(C2CCCCC2)c1=O Show InChI InChI=1S/C19H19Cl2N3O4/c20-10-6-13(21)16-12(17(18(26)27)22-14(16)7-10)8-23-9-15(25)24(19(23)28)11-4-2-1-3-5-11/h6-7,9,11,22,25H,1-5,8H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-Universität Curated by ChEMBL					Assay Description Tested for the affinity for the glycine binding site of the N-methyl-D-aspartate glutamate receptor using pig brain membranes in binding assay with [...				J Med Chem 46: 64-73 (2002) Article DOI: 10.1021/jm020955n BindingDB Entry DOI: 10.7270/Q2NZ8703
					More data for this Ligand-Target Pair