BDBM50122784 CHEMBL78621::Dimethyl-[4-(6-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-amine

SMILES: CN(C)c1ccc(cc1)-c1cn2cc(C)ccc2n1

InChI Key: InChIKey=IBKXGNZXXSHZQJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122784 (CHEMBL78621 | Dimethyl-[4-(6-methyl-imidazo[1,2-a]...) Show SMILES CN(C)c1ccc(cc1)-c1cn2cc(C)ccc2n1 Show InChI InChI=1S/C16H17N3/c1-12-4-9-16-17-15(11-19(16)10-12)13-5-7-14(8-6-13)18(2)3/h4-11H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	242	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates				J Med Chem 46: 237-43 (2003) Article DOI: 10.1021/jm020351j BindingDB Entry DOI: 10.7270/Q2WH2PBC
					More data for this Ligand-Target Pair