BDBM50122929 3-Amino-4-hydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide::CHEMBL334221
SMILES: CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1N)n1cnc2c(NCc3cccc(I)c3)ncnc12
InChI Key: InChIKey=IMLVDZRNXHKROA-MHMFGPJMSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM50122929 (3-Amino-4-hydroxy-5-[6-(3-iodo-benzylamino)-purin-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Binding affinity using [125I]-ABA against human Adenosine A3 receptor | J Med Chem 46: 353-5 (2003) Article DOI: 10.1021/jm0255724 BindingDB Entry DOI: 10.7270/Q2416WDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50122929 (3-Amino-4-hydroxy-5-[6-(3-iodo-benzylamino)-purin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Binding affinity using [125I]-ABA against human Adenosine A1 receptor | J Med Chem 46: 353-5 (2003) Article DOI: 10.1021/jm0255724 BindingDB Entry DOI: 10.7270/Q2416WDM | |||||||||||
More data for this Ligand-Target Pair |