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SMILES: Clc1cccc(Cl)c1Cc1n[nH]c(=O)c2ccccc12

InChI Key: InChIKey=DLWWYYGFYVWRIO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123007   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50123007 (CHEMBL3622589) Show SMILES Clc1cccc(Cl)c1Cc1n[nH]c(=O)c2ccccc12 Show InChI InChI=1S/C15H10Cl2N2O/c16-12-6-3-7-13(17)11(12)8-14-9-4-1-2-5-10(9)15(20)19-18-14/h1-7H,8H2,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintilla...				Eur J Med Chem 102: 310-9 (2015) BindingDB Entry DOI: 10.7270/Q2348N6H
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50123007 (CHEMBL3622589) Show SMILES Clc1cccc(Cl)c1Cc1n[nH]c(=O)c2ccccc12 Show InChI InChI=1S/C15H10Cl2N2O/c16-12-6-3-7-13(17)11(12)8-14-9-4-1-2-5-10(9)15(20)19-18-14/h1-7H,8H2,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) BindingDB Entry DOI: 10.7270/Q2348N6H
					More data for this Ligand-Target Pair