BDBM50123010 CHEMBL3622590

SMILES: Clc1ccc(Cl)c(Cc2n[nH]c(=O)c3ccccc23)c1Cl

InChI Key: InChIKey=NPOQEKKLANXSEV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50123010 (CHEMBL3622590) Show SMILES Clc1ccc(Cl)c(Cc2n[nH]c(=O)c3ccccc23)c1Cl Show InChI InChI=1S/C15H9Cl3N2O/c16-11-5-6-12(17)14(18)10(11)7-13-8-3-1-2-4-9(8)15(21)20-19-13/h1-6H,7H2,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintilla...				Eur J Med Chem 102: 310-9 (2015) BindingDB Entry DOI: 10.7270/Q2348N6H
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50123010 (CHEMBL3622590) Show SMILES Clc1ccc(Cl)c(Cc2n[nH]c(=O)c3ccccc23)c1Cl Show InChI InChI=1S/C15H9Cl3N2O/c16-11-5-6-12(17)14(18)10(11)7-13-8-3-1-2-4-9(8)15(21)20-19-13/h1-6H,7H2,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...				Eur J Med Chem 102: 310-9 (2015) BindingDB Entry DOI: 10.7270/Q2348N6H
					More data for this Ligand-Target Pair