BDBM50123208 2-(4-hydroxyphenyl)-3-methyl-1,2'-spirobi[1H-indene]-5-ol::CHEMBL145576

SMILES: CC1=C(c2ccc(O)cc2)C2(Cc3ccccc3C2)c2ccc(O)cc12

InChI Key: InChIKey=HXXGIDLDLCJJDB-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (RAT)	BDBM50123208 (2-(4-hydroxyphenyl)-3-methyl-1,2'-spirobi[1H-inden...) Show SMILES CC1=C(c2ccc(O)cc2)C2(Cc3ccccc3C2)c2ccc(O)cc12 |c:1| Show InChI InChI=1S/C24H20O2/c1-15-21-12-20(26)10-11-22(21)24(13-17-4-2-3-5-18(17)14-24)23(15)16-6-8-19(25)9-7-16/h2-12,25-26H,13-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Rat Estrogen receptor-alpha				Bioorg Med Chem Lett 13: 479-83 (2003) BindingDB Entry DOI: 10.7270/Q2F76BXK
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50123208 (2-(4-hydroxyphenyl)-3-methyl-1,2'-spirobi[1H-inden...) Show SMILES CC1=C(c2ccc(O)cc2)C2(Cc3ccccc3C2)c2ccc(O)cc12 |c:1| Show InChI InChI=1S/C24H20O2/c1-15-21-12-20(26)10-11-22(21)24(13-17-4-2-3-5-18(17)14-24)23(15)16-6-8-19(25)9-7-16/h2-12,25-26H,13-14H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Human Estrogen receptor-beta				Bioorg Med Chem Lett 13: 479-83 (2003) BindingDB Entry DOI: 10.7270/Q2F76BXK
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50123208 (2-(4-hydroxyphenyl)-3-methyl-1,2'-spirobi[1H-inden...) Show SMILES CC1=C(c2ccc(O)cc2)C2(Cc3ccccc3C2)c2ccc(O)cc12 |c:1| Show InChI InChI=1S/C24H20O2/c1-15-21-12-20(26)10-11-22(21)24(13-17-4-2-3-5-18(17)14-24)23(15)16-6-8-19(25)9-7-16/h2-12,25-26H,13-14H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Human Estrogen receptor-alpha				Bioorg Med Chem Lett 13: 479-83 (2003) BindingDB Entry DOI: 10.7270/Q2F76BXK
					More data for this Ligand-Target Pair
Estrogen receptor (Rattus norvegicus)	BDBM50123208 (2-(4-hydroxyphenyl)-3-methyl-1,2'-spirobi[1H-inden...) Show SMILES CC1=C(c2ccc(O)cc2)C2(Cc3ccccc3C2)c2ccc(O)cc12 |c:1| Show InChI InChI=1S/C24H20O2/c1-15-21-12-20(26)10-11-22(21)24(13-17-4-2-3-5-18(17)14-24)23(15)16-6-8-19(25)9-7-16/h2-12,25-26H,13-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity foor Rat Estrogen receptor-beta				Bioorg Med Chem Lett 13: 479-83 (2003) BindingDB Entry DOI: 10.7270/Q2F76BXK
					More data for this Ligand-Target Pair