BDBM50123210 2-phenyl-1,2'-spirobi[1H-indene]::CHEMBL345000

SMILES: C1c2ccccc2CC11C(=Cc2ccccc12)c1ccccc1

InChI Key: InChIKey=JDAYHXPHXPCKKX-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50123210 (2-phenyl-1,2'-spirobi[1H-indene] | CHEMBL345000) Show SMILES C1c2ccccc2CC11C(=Cc2ccccc12)c1ccccc1 |c:11| Show InChI InChI=1S/C23H18/c1-2-8-17(9-3-1)22-14-18-10-6-7-13-21(18)23(22)15-19-11-4-5-12-20(19)16-23/h1-14H,15-16H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Human Estrogen receptor-alpha				Bioorg Med Chem Lett 13: 479-83 (2003) BindingDB Entry DOI: 10.7270/Q2F76BXK
					More data for this Ligand-Target Pair
Estrogen receptor (Rattus norvegicus)	BDBM50123210 (2-phenyl-1,2'-spirobi[1H-indene] | CHEMBL345000) Show SMILES C1c2ccccc2CC11C(=Cc2ccccc12)c1ccccc1 |c:11| Show InChI InChI=1S/C23H18/c1-2-8-17(9-3-1)22-14-18-10-6-7-13-21(18)23(22)15-19-11-4-5-12-20(19)16-23/h1-14H,15-16H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity foor Rat Estrogen receptor-beta				Bioorg Med Chem Lett 13: 479-83 (2003) BindingDB Entry DOI: 10.7270/Q2F76BXK
					More data for this Ligand-Target Pair
Estrogen receptor (RAT)	BDBM50123210 (2-phenyl-1,2'-spirobi[1H-indene] | CHEMBL345000) Show SMILES C1c2ccccc2CC11C(=Cc2ccccc12)c1ccccc1 |c:11| Show InChI InChI=1S/C23H18/c1-2-8-17(9-3-1)22-14-18-10-6-7-13-21(18)23(22)15-19-11-4-5-12-20(19)16-23/h1-14H,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Rat Estrogen receptor-alpha				Bioorg Med Chem Lett 13: 479-83 (2003) BindingDB Entry DOI: 10.7270/Q2F76BXK
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50123210 (2-phenyl-1,2'-spirobi[1H-indene] | CHEMBL345000) Show SMILES C1c2ccccc2CC11C(=Cc2ccccc12)c1ccccc1 |c:11| Show InChI InChI=1S/C23H18/c1-2-8-17(9-3-1)22-14-18-10-6-7-13-21(18)23(22)15-19-11-4-5-12-20(19)16-23/h1-14H,15-16H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Human Estrogen receptor-beta				Bioorg Med Chem Lett 13: 479-83 (2003) BindingDB Entry DOI: 10.7270/Q2F76BXK
					More data for this Ligand-Target Pair