BDBM50123302 6,8-Dimethoxy-2-(3-morpholin-4-yl-propyl)-3-thioxo-2,3-dihydro-imidazo[1,5-a]indol-1-one::CHEMBL355913

SMILES: COc1cc(OC)c2cc3C(=O)N(CCCN4CCOCC4)C(=S)n3c2c1

InChI Key: InChIKey=RRQAVDSDZWOWAB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor receptor R1 (Homo sapiens (Human))	BDBM50123302 (6,8-Dimethoxy-2-(3-morpholin-4-yl-propyl)-3-thioxo...) Show SMILES COc1cc(OC)c2cc3C(=O)N(CCCN4CCOCC4)C(=S)n3c2c1 Show InChI InChI=1S/C19H23N3O4S/c1-24-13-10-15-14(17(11-13)25-2)12-16-18(23)21(19(27)22(15)16)5-3-4-20-6-8-26-9-7-20/h10-12H,3-9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TNF-alpha binding to TNFRc1				Bioorg Med Chem Lett 13: 533-8 (2003) BindingDB Entry DOI: 10.7270/Q2X929N3
					More data for this Ligand-Target Pair