BDBM50123308 3-Ethyl-2-thioxo-5-[1-[5-(2-trifluoromethyl-phenyl)-furan-2-yl]-meth-(Z)-ylidene]-thiazolidin-4-one::CHEMBL146955

SMILES: CCN1C(=S)S\C(=C/c2ccc(o2)-c2ccccc2C(F)(F)F)C1=O

InChI Key: InChIKey=KONUBAFTEZMEMT-ZROIWOOFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor receptor R1 (Homo sapiens (Human))	BDBM50123308 (3-Ethyl-2-thioxo-5-[1-[5-(2-trifluoromethyl-phenyl...) Show SMILES CCN1C(=S)S\C(=C/c2ccc(o2)-c2ccccc2C(F)(F)F)C1=O Show InChI InChI=1S/C17H12F3NO2S2/c1-2-21-15(22)14(25-16(21)24)9-10-7-8-13(23-10)11-5-3-4-6-12(11)17(18,19)20/h3-9H,2H2,1H3/b14-9-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TNF-alpha binding to TNFRc1				Bioorg Med Chem Lett 13: 533-8 (2003) BindingDB Entry DOI: 10.7270/Q2X929N3
					More data for this Ligand-Target Pair