BDBM50123346 2-(3-Hydroxy-indan-5-yl)-7-methoxy-6-oxazol-5-yl-1H-quinolin-4-one::CHEMBL153247

SMILES: COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1ccc2CCC(O)c2c1

InChI Key: InChIKey=FLGZEQZDTOBPEG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50123346 (2-(3-Hydroxy-indan-5-yl)-7-methoxy-6-oxazol-5-yl-1...) Show SMILES COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1ccc2CCC(O)c2c1 Show InChI InChI=1S/C22H18N2O4/c1-27-21-9-18-15(7-16(21)22-10-23-11-28-22)20(26)8-17(24-18)13-3-2-12-4-5-19(25)14(12)6-13/h2-3,6-11,19,25H,4-5H2,1H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb PRI Curated by ChEMBL					Assay Description Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II				Bioorg Med Chem Lett 13: 547-51 (2003) BindingDB Entry DOI: 10.7270/Q2NS0T7H
					More data for this Ligand-Target Pair