BDBM50123376 7-Methoxy-2-(3-methylamino-indan-5-yl)-6-oxazol-5-yl-1H-quinolin-4-one::CHEMBL357309

SMILES: CNC1CCc2ccc(cc12)-c1cc(O)c2cc(-c3cnco3)c(OC)cc2n1

InChI Key: InChIKey=RDIPHNSKCWONAH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123376   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50123376 (7-Methoxy-2-(3-methylamino-indan-5-yl)-6-oxazol-5-...) Show SMILES CNC1CCc2ccc(cc12)-c1cc(O)c2cc(-c3cnco3)c(OC)cc2n1 Show InChI InChI=1S/C23H21N3O3/c1-24-18-6-5-13-3-4-14(7-15(13)18)19-9-21(27)16-8-17(23-11-25-12-29-23)22(28-2)10-20(16)26-19/h3-4,7-12,18,24H,5-6H2,1-2H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb PRI Curated by ChEMBL					Assay Description Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II				Bioorg Med Chem Lett 13: 547-51 (2003) BindingDB Entry DOI: 10.7270/Q2NS0T7H
					More data for this Ligand-Target Pair