BDBM50123512 CHEMBL148258::[2'-(3-Methyl-butylcarbamoyl)-biphenyl-2-ylmethyl]-carbamic acid tert-butyl ester

SMILES: CC(C)CCNC(=O)c1ccccc1-c1ccccc1CNC(=O)OC(C)(C)C

InChI Key: InChIKey=HGUQKHLEQWUNSX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50123512 (CHEMBL148258 | [2'-(3-Methyl-butylcarbamoyl)-biphe...) Show SMILES CC(C)CCNC(=O)c1ccccc1-c1ccccc1CNC(=O)OC(C)(C)C Show InChI InChI=1S/C24H32N2O3/c1-17(2)14-15-25-22(27)21-13-9-8-12-20(21)19-11-7-6-10-18(19)16-26-23(28)29-24(3,4)5/h6-13,17H,14-16H2,1-5H3,(H,25,27)(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human voltage-gated potassium channel subunit Kv1.5 expressed in Xenopus oocytes				J Med Chem 46: 486-98 (2003) Article DOI: 10.1021/jm0210461 BindingDB Entry DOI: 10.7270/Q2RJ4HTF
					More data for this Ligand-Target Pair