BDBM50123765 CHEMBL158689::{2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-ylmethyl]-pyrrolo[3,2-c]pyridin-1-yl}-acetic acid methyl ester

SMILES: COC(=O)Cn1c(CN2CCN(CC2=O)S(=O)(=O)c2cc3ccc(Cl)cc3s2)cc2cnccc12

InChI Key: InChIKey=QTWOUIZTPSVGGJ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50123765 (CHEMBL158689 | {2-[4-(6-Chloro-benzo[b]thiophene-2...) Show SMILES COC(=O)Cn1c(CN2CCN(CC2=O)S(=O)(=O)c2cc3ccc(Cl)cc3s2)cc2cnccc12 Show InChI InChI=1S/C23H21ClN4O5S2/c1-33-22(30)14-28-18(8-16-11-25-5-4-19(16)28)12-26-6-7-27(13-21(26)29)35(31,32)23-9-15-2-3-17(24)10-20(15)34-23/h2-5,8-11H,6-7,12-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity for human Coagulation factor X				J Med Chem 46: 681-4 (2003) Article DOI: 10.1021/jm020384z BindingDB Entry DOI: 10.7270/Q2KW5FDH
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50123765 (CHEMBL158689 | {2-[4-(6-Chloro-benzo[b]thiophene-2...) Show SMILES COC(=O)Cn1c(CN2CCN(CC2=O)S(=O)(=O)c2cc3ccc(Cl)cc3s2)cc2cnccc12 Show InChI InChI=1S/C23H21ClN4O5S2/c1-33-22(30)14-28-18(8-16-11-25-5-4-19(16)28)12-26-6-7-27(13-21(26)29)35(31,32)23-9-15-2-3-17(24)10-20(15)34-23/h2-5,8-11H,6-7,12-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards trypsin				J Med Chem 46: 681-4 (2003) Article DOI: 10.1021/jm020384z BindingDB Entry DOI: 10.7270/Q2KW5FDH
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50123765 (CHEMBL158689 | {2-[4-(6-Chloro-benzo[b]thiophene-2...) Show SMILES COC(=O)Cn1c(CN2CCN(CC2=O)S(=O)(=O)c2cc3ccc(Cl)cc3s2)cc2cnccc12 Show InChI InChI=1S/C23H21ClN4O5S2/c1-33-22(30)14-28-18(8-16-11-25-5-4-19(16)28)12-26-6-7-27(13-21(26)29)35(31,32)23-9-15-2-3-17(24)10-20(15)34-23/h2-5,8-11H,6-7,12-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards thrombin				J Med Chem 46: 681-4 (2003) Article DOI: 10.1021/jm020384z BindingDB Entry DOI: 10.7270/Q2KW5FDH
					More data for this Ligand-Target Pair