BDBM50123906 (3-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarbamic acid O-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl] ester::CHEMBL348805
SMILES: Clc1cccc(c1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1
InChI Key: InChIKey=CQBLYIFHUKTOCD-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50123906 ((3-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarba...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a |
Università di Genova Curated by ChEMBL | Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method | J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX | |||||||||||
More data for this Ligand-Target Pair |