BDBM50123962 3-[4-(Biphenyl-4-sulfonylamino)-phenyl]-N-phenyl-acrylamide::CHEMBL168668

SMILES: O=C(Nc1ccccc1)\C=C\c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)cc1

InChI Key: InChIKey=MNXDDKPTUHZQGF-DEDYPNTBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50123962 (3-[4-(Biphenyl-4-sulfonylamino)-phenyl]-N-phenyl-a...) Show SMILES O=C(Nc1ccccc1)\C=C\c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C27H22N2O3S/c30-27(28-24-9-5-2-6-10-24)20-13-21-11-16-25(17-12-21)29-33(31,32)26-18-14-23(15-19-26)22-7-3-1-4-8-22/h1-20,29H,(H,28,30)/b20-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)				J Med Chem 46: 820-30 (2003) Article DOI: 10.1021/jm020377a BindingDB Entry DOI: 10.7270/Q22V2FG8
					More data for this Ligand-Target Pair