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SMILES: O=c1[nH]cc(C=Cc2ccccc2)c(=O)[nH]1

InChI Key: InChIKey=NTOQSTDCRZUSOD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124200   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydropyrimidine dehydrogenase [NADP(+)]


(Homo sapiens (Human))		BDBM50124200
PNG
(5-((E)-Styryl)-1H-pyrimidine-2,4-dione | CHEMBL352...)
Show SMILES O=c1[nH]cc(C=Cc2ccccc2)c(=O)[nH]1 |w:6.6|
Show InChI InChI=1S/C12H10N2O2/c15-11-10(8-13-12(16)14-11)7-6-9-4-2-1-3-5-9/h1-8H,(H2,13,14,15,16)
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n/an/a 43n/an/an/an/an/an/a



Nippon Roche Research Center

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)

Bioorg Med Chem Lett 13: 867-72 (2003)


BindingDB Entry DOI: 10.7270/Q21V5DBW
More data for this
Ligand-Target Pair