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SMILES: CCCCCc1cc2ccc(CCCCCN)cc2nc1N

InChI Key: InChIKey=CRQONYIBWLLTPH-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124218   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 8


(Homo sapiens (Human))		BDBM50124218
PNG
(CHEMBL3622862)
Show SMILES CCCCCc1cc2ccc(CCCCCN)cc2nc1N
Show InChI InChI=1S/C19H29N3/c1-2-3-5-9-17-14-16-11-10-15(8-6-4-7-12-20)13-18(16)22-19(17)21/h10-11,13-14H,2-9,12,20H2,1H3,(H2,21,22)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a 50n/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assay

J Med Chem 58: 7833-49 (2015)


BindingDB Entry DOI: 10.7270/Q2CF9RZK
More data for this
Ligand-Target Pair