BDBM50124562 1-[3-(4-isopropenylphenyl)-(2S,3S)-8-azabicyclo[3.2.1]oct-2-yl]-1-propanone::CHEMBL173344
SMILES: CCC(=O)[C@@H]1C2CCC(C[C@@H]1c1ccc(cc1)C(C)=C)N2
InChI Key: InChIKey=MKXUKRGNCYWSRF-AFNJWWOFSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50124562 (1-[3-(4-isopropenylphenyl)-(2S,3S)-8-azabicyclo[3....) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Binding affinity towards serotonin transporter (SERT) by using [3H]-paroxetine as radioligand | J Med Chem 46: 925-35 (2003) Article DOI: 10.1021/jm0100180 BindingDB Entry DOI: 10.7270/Q2W66K4V | |||||||||||
More data for this Ligand-Target Pair |