BDBM50124698 CHEMBL3621549

SMILES: Cc1c(Cl)nc(nc1NCc1ccoc1)C1CC1

InChI Key: InChIKey=RLIAZDJRMOVJHT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50124698 (CHEMBL3621549) Show SMILES Cc1c(Cl)nc(nc1NCc1ccoc1)C1CC1 Show InChI InChI=1S/C13H14ClN3O/c1-8-11(14)16-13(10-2-3-10)17-12(8)15-6-9-4-5-18-7-9/h4-5,7,10H,2-3,6H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human PDE10A2 transfected in AD293 cells by IMAP FP assay				J Med Chem 58: 7888-94 (2015) BindingDB Entry DOI: 10.7270/Q26Q202C
					More data for this Ligand-Target Pair