BDBM50124701 CHEMBL3621552

SMILES: Cc1c(Cl)nc(nc1NCc1cnn(C)c1)C1CC1

InChI Key: InChIKey=IEEHRLCNQKDBRL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124701   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50124701 (CHEMBL3621552) Show SMILES Cc1c(Cl)nc(nc1NCc1cnn(C)c1)C1CC1 Show InChI InChI=1S/C13H16ClN5/c1-8-11(14)17-13(10-3-4-10)18-12(8)15-5-9-6-16-19(2)7-9/h6-7,10H,3-5H2,1-2H3,(H,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human PDE10A2 transfected in AD293 cells by IMAP FP assay				J Med Chem 58: 7888-94 (2015) BindingDB Entry DOI: 10.7270/Q26Q202C
					More data for this Ligand-Target Pair