BDBM50124726 2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinonitrile::CHEMBL160642

SMILES: Clc1cccc(Cl)c1CSc1nc(C=O)ccc1C#N

InChI Key: InChIKey=ZIMDDBUYLJSPMR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50124726 (2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinon...) Show SMILES Clc1cccc(Cl)c1CSc1nc(C=O)ccc1C#N Show InChI InChI=1S/C14H8Cl2N2OS/c15-12-2-1-3-13(16)11(12)8-20-14-9(6-17)4-5-10(7-19)18-14/h1-5,7H,8H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory activity of compound against telomerase				Bioorg Med Chem Lett 13: 609-12 (2003) BindingDB Entry DOI: 10.7270/Q23R0S7S
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50124726 (2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinon...) Show SMILES Clc1cccc(Cl)c1CSc1nc(C=O)ccc1C#N Show InChI InChI=1S/C14H8Cl2N2OS/c15-12-2-1-3-13(16)11(12)8-20-14-9(6-17)4-5-10(7-19)18-14/h1-5,7H,8H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.13E+5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antiproliferative activity of compound against HT-29 (human colon caner ) cell line was determined by SRB assay				Bioorg Med Chem Lett 13: 609-12 (2003) BindingDB Entry DOI: 10.7270/Q23R0S7S
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50124726 (2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinon...) Show SMILES Clc1cccc(Cl)c1CSc1nc(C=O)ccc1C#N Show InChI InChI=1S/C14H8Cl2N2OS/c15-12-2-1-3-13(16)11(12)8-20-14-9(6-17)4-5-10(7-19)18-14/h1-5,7H,8H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antiproliferative activity of compound against HT-29 (human colon caner ) cell line was determined by SRB assay				Bioorg Med Chem Lett 13: 609-12 (2003) BindingDB Entry DOI: 10.7270/Q23R0S7S
					More data for this Ligand-Target Pair