Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50124726 (2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinon...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description In vitro antiproliferative activity of compound against HT-29 (human colon caner ) cell line was determined by SRB assay | Bioorg Med Chem Lett 13: 609-12 (2003) BindingDB Entry DOI: 10.7270/Q23R0S7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50124726 (2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinon...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 7.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description In vitro inhibitory activity of compound against telomerase | Bioorg Med Chem Lett 13: 609-12 (2003) BindingDB Entry DOI: 10.7270/Q23R0S7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50124726 (2-(2,6-Dichloro-benzylsulfanyl)-6-formyl-nicotinon...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.13E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description In vitro antiproliferative activity of compound against HT-29 (human colon caner ) cell line was determined by SRB assay | Bioorg Med Chem Lett 13: 609-12 (2003) BindingDB Entry DOI: 10.7270/Q23R0S7S | |||||||||||
More data for this Ligand-Target Pair |