BDBM50124949 (4-{(4-Bromo-phenyl)-[(Z)-methoxyimino]-methyl}-4'-methyl-[1,4']bipiperidinyl-1'-yl)-(4,6-dimethyl-pyrimidin-5-yl)-methanone::CHEMBL161587

SMILES: CO\N=C(\C1CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C)c1ccc(Br)cc1

InChI Key: InChIKey=YOVJVIUBJPWGOX-BGABXYSRSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124949   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50124949 ((4-{(4-Bromo-phenyl)-[(Z)-methoxyimino]-methyl}-4'...) Show SMILES CO\N=C(\C1CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C)c1ccc(Br)cc1 Show InChI InChI=1S/C26H34BrN5O2/c1-18-23(19(2)29-17-28-18)25(33)31-15-11-26(3,12-16-31)32-13-9-21(10-14-32)24(30-34-4)20-5-7-22(27)8-6-20/h5-8,17,21H,9-16H2,1-4H3/b30-24+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]RANTES binding to CCR5 receptor.				Bioorg Med Chem Lett 13: 709-12 (2003) BindingDB Entry DOI: 10.7270/Q2VM4CTD
					More data for this Ligand-Target Pair