BDBM50125023 (R)-N-{[4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-methyl}-3-phenyl-2-phenylmethanesulfonylamino-propionamide::CHEMBL162710
SMILES: NC(=N)NCCCC(NC(=O)CNC(=O)[C@@H](Cc1ccccc1)NS(=O)(=O)Cc1ccccc1)C(=O)c1nccs1
InChI Key: InChIKey=PYAQKASZZJANHS-FOIFJWKZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50125023 ((R)-N-{[4-Guanidino-1-(thiazole-2-carbonyl)-butylc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against factor Xa | Bioorg Med Chem Lett 13: 729-32 (2003) BindingDB Entry DOI: 10.7270/Q2T72GTS | |||||||||||
More data for this Ligand-Target Pair |