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SMILES: CN(Cc1ccc2ccccc2c1)c1ccc(cn1)C(Cc1cc[n+]([O-])cc1)c1ccc(OC(F)F)c(OC(F)F)c1

InChI Key: InChIKey=WUFNRPZFAQJKKI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125074   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A


(Homo sapiens (Human))		BDBM50125074
PNG
(CHEMBL444865 | {5-[1-(3,4-Bis-difluoromethoxy-phen...)
Show SMILES CN(Cc1ccc2ccccc2c1)c1ccc(cn1)C(Cc1cc[n+]([O-])cc1)c1ccc(OC(F)F)c(OC(F)F)c1
Show InChI InChI=1S/C32H27F4N3O3/c1-38(20-22-6-7-23-4-2-3-5-24(23)16-22)30-11-9-26(19-37-30)27(17-21-12-14-39(40)15-13-21)25-8-10-28(41-31(33)34)29(18-25)42-32(35)36/h2-16,18-19,27,31-32H,17,20H2,1H3
PDB
MMDB

KEGG

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antibodypedia
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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.5n/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in...

Bioorg Med Chem Lett 13: 741-4 (2003)


BindingDB Entry DOI: 10.7270/Q2PG1R3G
More data for this
Ligand-Target Pair