null

SMILES: OCCN1CCc2c([nH]c3ccccc23)C1c1ccc(Cl)cc1

InChI Key: InChIKey=KJENGQHGPDRMLH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50125086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50125086 (CHEMBL3622992) Show SMILES OCCN1CCc2c([nH]c3ccccc23)C1c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c20-14-7-5-13(6-8-14)19-18-16(9-10-22(19)11-12-23)15-3-1-2-4-17(15)21-18/h1-8,19,21,23H,9-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human MCF cells assessed as estradiol-induced receptor response				J Med Chem 58: 8128-40 (2015) BindingDB Entry DOI: 10.7270/Q2F76FCN
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50125086 (CHEMBL3622992) Show SMILES OCCN1CCc2c([nH]c3ccccc23)C1c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c20-14-7-5-13(6-8-14)19-18-16(9-10-22(19)11-12-23)15-3-1-2-4-17(15)21-18/h1-8,19,21,23H,9-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at progesterone receptor in human MCF7 cells				J Med Chem 58: 8128-40 (2015) BindingDB Entry DOI: 10.7270/Q2F76FCN
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50125086 (CHEMBL3622992) Show SMILES OCCN1CCc2c([nH]c3ccccc23)C1c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c20-14-7-5-13(6-8-14)19-18-16(9-10-22(19)11-12-23)15-3-1-2-4-17(15)21-18/h1-8,19,21,23H,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at ERalpha receptor in human MCF7 cells				J Med Chem 58: 8128-40 (2015) BindingDB Entry DOI: 10.7270/Q2F76FCN
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50125086 (CHEMBL3622992) Show SMILES OCCN1CCc2c([nH]c3ccccc23)C1c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c20-14-7-5-13(6-8-14)19-18-16(9-10-22(19)11-12-23)15-3-1-2-4-17(15)21-18/h1-8,19,21,23H,9-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	<3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to glucocorticoid receptor (unknown origin)				J Med Chem 58: 8128-40 (2015) BindingDB Entry DOI: 10.7270/Q2F76FCN
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50125086 (CHEMBL3622992) Show SMILES OCCN1CCc2c([nH]c3ccccc23)C1c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c20-14-7-5-13(6-8-14)19-18-16(9-10-22(19)11-12-23)15-3-1-2-4-17(15)21-18/h1-8,19,21,23H,9-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	<3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to androgen receptor (unknown origin)				J Med Chem 58: 8128-40 (2015) BindingDB Entry DOI: 10.7270/Q2F76FCN
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50125086 (CHEMBL3622992) Show SMILES OCCN1CCc2c([nH]c3ccccc23)C1c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c20-14-7-5-13(6-8-14)19-18-16(9-10-22(19)11-12-23)15-3-1-2-4-17(15)21-18/h1-8,19,21,23H,9-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	<3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor (unknown origin)				J Med Chem 58: 8128-40 (2015) BindingDB Entry DOI: 10.7270/Q2F76FCN
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50125086 (CHEMBL3622992) Show SMILES OCCN1CCc2c([nH]c3ccccc23)C1c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c20-14-7-5-13(6-8-14)19-18-16(9-10-22(19)11-12-23)15-3-1-2-4-17(15)21-18/h1-8,19,21,23H,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to ERalpha receptor (unknown origin)				J Med Chem 58: 8128-40 (2015) BindingDB Entry DOI: 10.7270/Q2F76FCN
					More data for this Ligand-Target Pair