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SMILES: [O-][N+](=O)c1ccccc1-c1ccc(o1)C(=O)N1CCc2c([nH]c3ccccc23)C1c1ccc2OCOc2c1

InChI Key: InChIKey=XYXNYAJEWNAPAN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125137   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50125137
PNG
((1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-c...)
Show SMILES [O-][N+](=O)c1ccccc1-c1ccc(o1)C(=O)N1CCc2c([nH]c3ccccc23)C1c1ccc2OCOc2c1
Show InChI InChI=1S/C29H21N3O6/c33-29(25-12-11-23(38-25)20-6-2-4-8-22(20)32(34)35)31-14-13-19-18-5-1-3-7-21(18)30-27(19)28(31)17-9-10-24-26(15-17)37-16-36-24/h1-12,15,28,30H,13-14,16H2
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PubMed
 219n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development L.L.C.

Curated by ChEMBL


Assay Description
Inhibitory activity against PDE5 from human corpus cavernosum

Bioorg Med Chem Lett 13: 761-5 (2003)


BindingDB Entry DOI: 10.7270/Q29886CM
More data for this
Ligand-Target Pair