BDBM50125271 CHEMBL10864::N-(4'-Chloro-biphenyl-4-ylmethyl)-N-(2-diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulfanyl)-4-oxo-4H-pyrimidin-1-yl]-acetamide

SMILES: CCN(CC)CCN(Cc1ccc(cc1)-c1ccc(Cl)cc1)C(=O)Cn1ccc(=O)nc1SCc1ccc(F)cc1

InChI Key: InChIKey=HOHKLBBSZBYNQP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125271   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50125271 (CHEMBL10864 | N-(4'-Chloro-biphenyl-4-ylmethyl)-N-...) Show SMILES CCN(CC)CCN(Cc1ccc(cc1)-c1ccc(Cl)cc1)C(=O)Cn1ccc(=O)nc1SCc1ccc(F)cc1 Show InChI InChI=1S/C32H34ClFN4O2S/c1-3-36(4-2)19-20-37(21-24-5-9-26(10-6-24)27-11-13-28(33)14-12-27)31(40)22-38-18-17-30(39)35-32(38)41-23-25-7-15-29(34)16-8-25/h5-18H,3-4,19-23H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Lp-PLA2				Bioorg Med Chem Lett 13: 1067-70 (2003) BindingDB Entry DOI: 10.7270/Q2S75FPD
					More data for this Ligand-Target Pair