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SMILES: C(Cn1cnc2cccnc12)Oc1ccc(Cc2ccccc2)cc1

InChI Key: InChIKey=NWOUKUYIHNVVRG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125422   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50125422
PNG
(3-[2-(4-Benzyl-phenoxy)-ethyl]-3H-imidazo[4,5-b]py...)
Show SMILES C(Cn1cnc2cccnc12)Oc1ccc(Cc2ccccc2)cc1
Show InChI InChI=1S/C21H19N3O/c1-2-5-17(6-3-1)15-18-8-10-19(11-9-18)25-14-13-24-16-23-20-7-4-12-22-21(20)24/h1-12,16H,13-15H2
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n/an/a>3.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of recombinant human leukotriene A4 hydrolase.

Bioorg Med Chem Lett 13: 1137-9 (2003)


BindingDB Entry DOI: 10.7270/Q2891587
More data for this
Ligand-Target Pair