BDBM50125426 3-[2-(4-Benzyl-phenoxy)-ethyl]-3H-purine::CHEMBL14547
SMILES: C(Cn1cncc2ncnc12)Oc1ccc(Cc2ccccc2)cc1
InChI Key: InChIKey=YLVHOIHLBUELSW-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50125426 (3-[2-(4-Benzyl-phenoxy)-ethyl]-3H-purine | CHEMBL1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of recombinant human leukotriene A4 hydrolase. | Bioorg Med Chem Lett 13: 1137-9 (2003) BindingDB Entry DOI: 10.7270/Q2891587 | |||||||||||
More data for this Ligand-Target Pair |